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Opening Remarks/How the Brain Invents the Mind

Dr. Susan Hockfield Rebecca Saxe Ph.D. '03: June 6, 2009; Running Time: 1:39:22

About the Lecture

About the Lecture

In trying financial times, Susan Hockfield remains optimistic and committed to pursuing MIT’s massive, multi-year initiatives in energy and life sciences. She prefaces her “whirlwind” tour of MIT for an alumni audience by referencing the campus-wide relief at the change in presidential administrations, which promises to make science and engineering more central, and to make “MIT values more mainstream.” If it indeed becomes “cool to be smart,” Hockfield believes MIT can count on taking a prominent national role in research, policy and education.

One key area in which MIT hopes to make a major contribution is sustainable energy. The MIT Energy Initiative, two years old, brings together faculty and students across all disciplines to develop a portfolio of new technologies (although the focus seems increasingly to fall on solar). Campus interest is so intense that the Institute has committed to a minor in energy, and it’s seeking five new professorships in the area. The other major enterprise involves fusing biological sciences with engineering, especially in the study of cancer. At the new Koch Institute, cancer biologists and engineers have already made “fundamental discoveries underlying new targeted cancer drugs,” and they are hard at work decoding the disease, and devising new methods for diagnosis and treatment.

Hockfield also candidly describes the impact of the economic downturn on the Institute, acknowledging that “most revenue streams have been compromised,” except for research. With the endowment down by 20-25%, departments across the board are making significant but strategic cuts for the next two to three years. MIT will not compromise on providing financial aid to needy students, a cost that understandably has risen in the past year, nor on hiring faculty. Hockfield hopes that private philanthropy will help MIT “preserve core strengths and values.” At the end of the recession, she says, “We want to come out with a leaner, stronger Institute.”

Fellow neuroscientist Rebecca Saxe outlines her research investigating the neural basis for a Theory of Mind -- how the human mind seems geared to “glean what others are thinking and feeling.” From her work with children and adults, Saxe has determined that there’s a very specific region of the brain -- the right temporal-parietal junction -- dedicated to thinking about how others think. This area lights up in the fMRI scanner when people read stories involving another person’s beliefs and moral judgments, but not when they digest other kinds of written material. The RTPJ develops this special function slowly (young children don’t have it), and Saxe has discovered that she can interfere with this region’s activities, altering her subjects’ sense of what constitutes morally permissible behavior. She’s exploring whether these distinct neural networks develop differently in children with autism, with the hope of finding therapies that might someday help treat the disorder.

Lecture Details

Location: Kresge Auditorium

“There’s a new administration in Washington, one that values science, analysis, and research... We hope that it will be cool to be smart.”

Susan Hockfield

About the Speakers

Dr. Susan Hockfield

MIT President
Professor of Neuroscience

Susan Hockfield has served as the sixteenth president of MIT since December 2004. A strong advocate of the vital role that science, technology, and the research university play in the world, she believes that MIT can best advance its historic mission of teaching, research, and service by providing robust and sustained support for the ideas and energies of its faculty and students.

A noted neuroscientist whose research has focused on the development of the brain, Dr. Hockfield is the first life scientist to lead MIT and holds a faculty appointment as professor of neuroscience in the Institute's Department of Brain and Cognitive Sciences.

Under her leadership, MIT has launched a major Institute-wide initiative in energy research and education and continues to expand its activities at the intersection of the life sciences and engineering, with a particular focus on cancer research. The Institute has also embarked on a sustained effort to strengthen support for student life and learning, including undergraduate curriculum renewal, and is undertaking major campus construction and renovation projects with a combined value of approximately three-quarters of a billion dollars.

Before assuming the presidency of MIT, Dr. Hockfield was the William Edward Gilbert Professor of Neurobiology and provost at Yale University. She joined the Yale faculty in 1985 and was named full professor in 1994. While at Yale, she played a central role in the university's leadership, first as dean of its Graduate School of Arts and Sciences (1998-2002), with oversight of more than 70 graduate programs, and then as provost, the university's chief academic and administrative officer.

Dr. Hockfield earned her B.A. in biology from the University of Rochester and a Ph.D. from the Georgetown University School of Medicine, while carrying out her dissertation research in neuroscience at the National Institutes of Health (NIH). She was an NIH postdoctoral fellow at the University of California at San Francisco in 1979-80, and then joined the scientific staff at the Cold Spring Harbor Laboratory in New York in 1980. She served as director of the Laboratory's Summer Neurobiology Program from 1985 to 1997, concurrent with her teaching post at Yale, and more recently as a trustee of the laboratory. Her memberships in professional societies include the American Association for the Advancement of Science and the Society for Neuroscience.

Rebecca Saxe Ph.D. '03

Assistant Professor of Cognitive Neuroscience
Fred and Carole Middleton Career Development Professorship, Department of Brain and Cognitive Sciences, MIT

Rebecca Saxe became an assistant professor at MIT in 2006. That same year, she was named a Kavli Fellow, National Academy of Sciences. In 2008, she received the Cognitive Neuroscience Society Young Investigator Award. In 2009, she received the Robert L. Fantz Award for Young Psychologists. She was a Junior Fellow, in the Society of Fellows, Harvard University, from 2003 to 2006.

Saxe received her Ph.D. in Cognitive Science in 2003 from MIT, and earned a B.A. in Psychology and Philosophy from Oxford University.

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