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HOST:
Whitehead Institute for Biomedical Research




How Cancer Begins
Robert A. Weinberg, ‘64, PhD ‘69
September 23, 2003
12:00 PM


LOCATION:
10-250



   
Video Time Index
How Cancer Begins

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SPEAKER:
Robert A. Weinberg, ‘64, PhD ‘69
Founding Member, MIT Center for Cancer Research
Member, Whitehead Institute
Daniel K. Ludwig and American Cancer Society Professor for Cancer Research
Department of Biology


ABOUT THE LECTURE:
If you’re worried about getting cancer, do yourself a favor: steer clear of red meat and rich foods, and avoid cigarettes. In this lecture, Robert Weinberg provides the scientific basis for this commonplace advice, as well as a layman’s look at the genetic, biochemical and environmental factors that make good cells go bad.

Normal cells are civic-minded, lining up together in a precise architecture that gives structure to body tissue. When the cell’s genes are damaged, they send out faulty instructions, turning orderly structure into a chaotic mess. This kind of injury to cells likely comes from the outside – as many as 90% of human cancers are due to bad diets and smoking. Weinberg wants to understand the specific pathways by which the cells’ enemies invade and do their damage, in hopes of then being able to halt the process and freeze a cancer’s growth. But, cautions Weinberg, better to count on prevention than a cure in the fight against cancer.

ABOUT THE SPEAKER:
Robert A. Weinberg has earned some of the top honors in his field. Most recently, he won the 2006 Landon-AACR Prize for Basic and Translational Cancer Research. He is also a 1997 National Medal of Science awardee.

Weinberg's laboratory discovered the first human oncogene and the first tumor suppressor gene. Today, much of his research focuses on new models of breast cancer development including the stages of tumor invasiveness and metastasis.

He earned his Ph.D. in biology from MIT in 1969, and was one of the Founding Members of the MIT Center for Cancer Research in 1973. He was appointed a professor at MIT in 1982, the same year he joined the Whitehead Institute. Weinberg was named American Cancer Society Research Professor in 1985 and received the Daniel K. Ludwig Professorship for Cancer Research in 1997. He is a member of the National Academy of Sciences and the Institute of Medicine.

Weinberg's Whitehead website
Weinberg's CCR website
MIT Biology Department page

NOTES ON THE VIDEO (Time Index):
Weinberg is introduced by John Pratt, Associate Director, Whitehead Institute.

There is a brief period of audio level adjustment as Weinberg begins his talk. The trouble begins at 1:20. If you skip ahead to 2:37, you can bypass these technical difficulties, and not miss any content.

Video length is 59:42.

Q&A begins at 46:00.

 
 

The information on this page was accurate as of the day the video was added to MIT World. This video was added to MIT World on 2003-10-16.

       

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